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MLB Picks

Baltimore Orioles vs. Boston Red Sox Odds, Picks, and Predictions

American League East division rivals the Baltimore Orioles and Boston Red Sox meet on Monday night in the first game of a four-game series.

This is the final series of the 2022 MLB season between the Orioles and Red Sox. The Baltimore Orioles hold the head-to-head season series 8-7.

Baltimore desperately needs to win to prolong their playoff hopes, while Boston has lost their last five games and is playing out the remainder of the 2022 MLB season.

MLB Injury Report

You won’t need to review the MLB injury report to make a pick in this game, although Boston has notable names on the injury report.

We’ll check the Orioles vs. Red Sox odds to find the best selection for your betting ticket today. The first pitch for the Orioles vs. Red Sox is scheduled for 7:10 P.M. ET from legendary Fenway Park in Boston, Massachusetts.

Orioles vs. Red Sox Odds Breakdown

Red Sox Odds Breakdown

Before making any Orioles vs Red Sox picks, we need to review the odds. Online sportsbooks have the odds set with the Boston Red Sox as the unexpected betting favorite, listed between -123 and -135 on the money line.

The Baltimore Orioles are listed as the unconvincing underdog on the money line between +110 and +114.

Most online sportsbooks have Boston (-1.5) as the betting underdog on the run line spread, with odds listed between +140 and +160.

Orioles Odds Breakdown

The Baltimore Orioles odds (+1.5) have them as the betting favorite on the run line spread on most sportsbooks, listed between -169 and -196.

If you want to include total runs wagers with your other Orioles vs Red Sox picks, online sports books have the total runs listed at either 9.5.

The over is listed with odds between -108 and -115, while the under is listed with odds between +100 and -110.

Baltimore Orioles vs. Boston Red Sox Betting Preview

The Baltimore Orioles enter Monday’s game with a 79–73 record (.520 winning percentage). The Orioles are hanging onto the American League Wild Card chase, but their chances are fading fast as the MLB season closes.

Orioles Averaging Numbers

The Baltimore Orioles have a 4-6 record in their last ten games, averaging 4.2 runs per game, raising their season average to 4.18.

In this same stretch, the Orioles have averaged 4.8 opposition runs per game, raising their season average to 4.18 runs per game. 

The Boston Red Sox enter Monday’s game against the Orioles with a 72-80 record (.474 winning percentage).

The Red Sox standings make it clear that Boston has been eliminated from playoff contention for some time.

Red Sox Averaging Numbers

The Boston Red Sox are 3-7 in their last ten games, averaging 3.7 runs per game, dropping their season average to 4.52.

Over this same ten-game stretch, the Red Sox have surrendered 4.5 runs per game to opposing hitters, bringing their season average to 4.80 runs per game.

MLB Stats

According to MLB stats, the Baltimore Orioles hold an 8-7 lead in the 2022 head-to-head season series with the Boston Red Sox.

Of these fifteen games, only five have finished with a one-run spread. This information should be factored into any Orioles vs Red Sox picks.

Starting Pitchers:

Baltimore Orioles 

The Baltimore Orioles have right-handed pitcher Jordan Lyles scheduled to start Monday night’s matchup in Boston. Lyles has an 11-11 record in thirty appearances, pitching to a 4.50 ERA and a 1.39 WHIP

The Orioles have won four of Lyles’ last six appearances and seven of his previous ten. All but one of Lyles’ appearances finished covering the run line spread in these ten appearances.

Boston Red Sox 

The Boston Red Sox have right-handed pitcher Connor Seabold scheduled to throw the first pitch against the Orioles at Fenway Park on Monday night. Seabold has a 0-3 record in 4 appearances, pitching to a 10.47 ERA and a 2.20 WHIP. 

The Red Sox have won only one of Seabold’s appearances: an extra-innings win over the Chicago Cubs on July 3rd. None of Seabold’s four appearances have finished within a one-run spread, and Seabold has not pitched passed the fifth inning in any start this season.

Orioles vs. Red Sox Picks and Predictions

Statistically speaking, we’re picking Baltimore in every angle on our Orioles vs Red Sox picks. We’re picking the Orioles to win on the moneyline on Monday night in Boston (+110 to +114).

Everything we can analyze suggests that the Orioles should win this game. However, Boston and Baltimore have played each other close, essentially splitting the head-to-head season series, with one-third of their games decided by a one-run spread.

Any moneyline-based Orioles vs Red Sox picks can be combined with a run line wager. Again, we’re taking the Orioles on the run line on our Orioles vs Red Sox picks.

The Orioles are the favorite on-betting run line betting lines (-169 and -196) which aren’t the best odds.

Most Profitable Team for this Matchup

Still, if you are taking Baltimore in your picks, you’ll likely want to parlay any Orioles on the run line pick with Baltimore’s favorable odds on the money line. 

Combining recent performance and reviewing the statistics, there is nothing that gives us the confidence to pick the Boston Red Sox against the Baltimore Orioles.

If we’re making one pick for our Orioles vs. Red Sox picks today, we’re taking the Baltimore Orioles on the moneyline.

MLB Pick: Orioles (+112)

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