The Arizona Cardinals will take on the San Francisco 49ers in an NFC West matchup inside of Levi’s Stadium on Sunday afternoon. The Cardinals are leading the division with a 7-1 record and are coming off a 24-21 home loss against the Green Bay Packers.
Kyler Murray finished 22-of-33 for 274 yards with a pair of interceptions. The 49ers are third in the division with a 3-4 record and are coming off a 33-22 road win over the Chicago Bears. Jimmy Garoppolo went 17-of-28 for 322 yards.
Arizona Cardinals Preview: Top Pass Catcher
Wide receiver DeAndre Hopkins is listed as questionable for this game with a hamstring injury but is one of the best in the game. On the season, Hopkins has 35 receptions for 486 yards (13.9 yards per catch) with five touchdowns. In his last game against the Packers, he had a pair of catches on two targets for 66 yards (33 yards per reception).
The Arizona Cardinals have been a spectacular defensive team as they are giving up 17.3 points per game this year. In their previous game against the Green Bay Packers, the Cards allowed 24 points on 335 total yards of offense (184 passing, 151 rushing).
The defense did a solid job as the Packers went 6-of-14 on third down tries and 2-of-4 on fourth down attempts. They limited Aaron Rodgers as Green Bay went just 4.8 passing yards per attempt. If the defense can continue to step up against a lesser offense, it will really be a good sign for Arizona here.
San Francisco 49ers Preview: EM Finding TDs
Running back Elijah Mitchell has been doing well as he has 81 rushing attempts for 433 yards (5.3 yards per carry) with three rushing touchdowns. He is listed as questionable with a ribs injury for this game. In his last game against the Bears, Mitchell had a great game going 18 rushes for 137 yards (7.6 yards per run) with a touchdown.
The San Francisco 49ers have been a good defensive unit thus far as they are allowing 24.4 points per game. In their previous game against the Chicago Bears, San Fran gave up 22 points on 324 total yards of offense (148 passing, 176 rushing).
The 49ers need to improve at stopping first downs as the Bears went 8-of-15 on third down and converted their only fourth-down attempt. San Francisco needs to improve on stopping the run as Chicago averaged 4.9 rushing yards per attempt.
Who to Bet on Cardinals at 49ers
The Arizona Cardinals are the better team both on the field and in the betting markets compared to the San Francisco 49ers. The Cardinals are 6-2 against the spread this season, while the 49ers are 2-5 against the spread in their own right.
In terms of just outright wins and losses, Arizona is a perfect 4-0 on the road while San Francisco is 0-3 at home. The Cardinals are dealing with some injuries, but the 49ers are not doing well offensively as in his last four games, Jimmy Garoppolo has four touchdowns and four interceptions.
These teams played less than a month ago, and the Cardinals won 17-10, so they have a game plan for one another in this matchup. All in all, go with the Arizona Cardinals getting points on the road here from all of the top sportsbooks in the country against the San Francisco 49ers.