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Home▷NFL Picks▷Denver Broncos vs. San Francisco 49ers Betting Picks and Prediction

Denver Broncos vs. San Francisco 49ers Betting Picks and Prediction

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Don’t think San Francisco 49ers coach Kyle Shanahan is interested in discussing the struggles of Denver Broncos quarterback Russell Wilson.

When Shanahan has crossed paths with Wilson, it usually hasn’t ended well for Shanahan. When Wilson was with Seattle, he was 2-8 when leading Seattle against San Francisco.

However, none of that means anything now. When it comes to making Broncos vs. 49ers betting picks, San Francisco and Denver are both in different places.

The 49ers are hoping that Jimmy Garoppolo can recapture some of his old magic and get San Francisco started on a winning streak. Denver hasn’t quite found its legs with a new quarterback and coach in charge.

While it is highly probable the Broncos will get their act together, it is something they will have to prove in the win column. Early-season returns have been ugly for Denver thus far.

San Francisco 49ers vs. Denver Broncos

When making Broncos vs. 49ers betting picks, it is important to understand where each team is right now. Denver quarterback Russell Wilson has only thrown two touchdowns in two games, and many believe he is being held back by rookie coach Nathaniel Hackett.

However, NFL stats show that Wilson is a veteran player who has worked with less before. San Francisco suffered a loss last week when quarterback Trey Lance broke his ankle and is now out for the season.

However, the 49ers are uniquely prepared for such a scenario. San Francisco wasn’t able to deal with Garoppalo in the offseason and was left with a solid veteran backup quarterback.

Understandably, there is confidence San Francisco can contend with the veteran QB under center.

Broncos vs. 49ers Matchup Info

Denver will host this game at 8:20 p.m. Sunday at Empower Field at Mile High.

Denver Performance

Broncos odds show Denver is a team that is seeking balance on offense. Running backs Javante Williams and Melvin Gordon III have both received exactly 22 carries each and have produced 118 and 105 yards, respectively.

However, both lost key fumbles in the season opener that would come back to haunt the Broncos.

Key Injuries

  • WR Tyrie Cleveland questionable (hamstring)
  • WR K.J. Hamler questionable (knee/hip)
  • DT Miike Purcell questionable
  • DE Dre’Mont Jones questionable
  • WE Jerry Jeudy questionable (ribs/shoulder)

Betting Trends

  • The Broncos are 0-2 against the spread.
  • The over is 0-2 in Denver’s games this season.

San Francisco 49ers

Garoppolo was practicing by himself in a field during training camp. Now, he’s behind the wheel for San Francisco’s playoff hopes.

Against Seattle last week, the veteran quarterback completed 13-of-21 passes for 154 yards and a touchdown.

When it comes to the 49ers game today, San Francisco will want to control Denver by using a balanced offense to grab a win.

When it comes to NFL player stats, the 49ers don’t have a dominant rusher. Jeff Wilson and Deebo Samuel are the team’s two leading runners so far this season. 

Key Injuries

  • OT Colton McKivitz questionable 
  • TE George Kittle questionable (groin)
  • DE Arik Armstead questionable (football)

Betting Trends

  • San Francisco is 1-1 against the spread.
  • The over is 0-2 in the 49ers’ games this season.

Broncos vs. 49ers Odds Breakdown

Anyone making Broncos vs. 49ers betting picks shows San Francisco is a 2-point road favorite. The 49ers are -125 on the Moneyline, while the Broncos are +110. The over/under is set at 44.5 points.

Denver vs. San Francisco betting picks

This game will be a strong one that should be closely contested. Both NFL teams are off to 1-1 starts, and there isn’t too much theory that separates them. When a game is this close, it is preferable to take the slight home underdog at plus money.

Denver’s offense is desperate to break out. However, turnovers and other struggles have held them back before. San Francisco’s defense is hoping to take advantage of Denver’s early struggles and beat them.

The Denver Broncos and San Francisco 49ers is a game that should swing back and forth. This is a game where Denver should feel comfortable moving the ball. Each team will find their way over the 30point mark and send this total over.

Denver vs. San Francisco Score Prediction

Denver 24, San Francisco 21

NFL Pick: Broncos +1 (+100)

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More Related to Broncos vs 49ers

  • Denver Broncos Season Odds, Props and Futures
  • San Francisco 49ers Season Odds, Props and Futures
#Denver Broncos
#NFL
#San Francisco 49ers
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