The Indianapolis Colts will travel to Highmark Stadium on Sunday afternoon to take on the Buffalo Bills in an AFC matchup.
The Colts are second in the AFC South with a 5-5 record and are riding a two-game winning streak after defeating the Jacksonville Jaguars 23-17. Carson Wentz went 22-of-34 for 180 yards.
The Bills are leading the AFC East with a 6-3 record and are coming off a 45-17 road win over the New York Jets. Josh Allen finished going 21-of-28 for 366 yards with two touchdowns and an interception.
Colts at Bills Betting Analysis
On the Indianapolis Colts side
Running back Jonathan Taylor has been dominant on the ground this season as he has 161 carries for 937 rushing yards (5.8 yards per attempt) with nine rushing touchdowns as well as 29 receptions for 303 yards (10.4 yards per catch) with a receiving touchdown.
In his last game against the Jags, Taylor ran 21 times for 116 yards (5.5 yards per rush) with a rushing touchdown with six catches for 10 yards (1.7 yards per reception).
The Indianapolis Colts have been doing pretty well defensively this season as they are giving up 23 points per game. In their previous game against the Jacksonville Jaguars, Indy allowed 17 points on 331 total yards of offense (152 passing, 179 rushing).
The Colts did a good job as the Jaguars went 5-of-15 on third down attempts. Jacksonville was definitely able to run the football well as they finished averaging 7.5 rushing yards per attempt.
On the Buffalo Bills side
Wide receiver Stefon Diggs has been playing extremely well this season as he has 56 catches on 86 targets for 750 yards (13.4 yards per reception) with four receiving touchdowns so far.
In his last game against the Jets, Diggs finished with eight receptions on 13 targets for 162 yards (20.3 yards per catch) with a receiving touchdown.
The Buffalo Bills have been dominant on defense this year as they are allowing 15 points per game. In their previous game against the New York Jets, Buffalo gave up 17 points on 366 total yards of offense (296 passing, 70 rushing).
The Bills were able to force five turnovers (one fumble recovery, four interceptions). Buffalo also were able to stop the running game well enough as New York averaged 3.2 rushing yards per attempt.
Colts at Bills Prediction
Looking at the top sportsbooks across the United States, the Buffalo Bills are a touchdown favorite at home here. Buffalo is giving up 12.3 points in their previous three games, while Indianapolis has allowed 24.8 points in their last four games.
I also trust Josh Allen to limit turnovers over Carson Wentz, despite throwing more interceptions this season. The Colts are 1-3-1 against the spread in their last five road games against the Bills.
All in all, go with the Buffalo Bills to cover the spread here.
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