The San Francisco 49ers will travel to Nissan Stadium on Thursday night to take on the Tennessee Titans in a non-conference matchup.
The 49ers are third in the NFC West with an 8-6 record and are riding a two-game winning streak after defeating the Atlanta Falcons at home 31-13. Jimmy Garoppolo went 18-of-23 for 235 yards with a touchdown.
The Titans are leading the AFC South with a 9-5 record and are coming off a road loss to the Pittsburgh Steelers 19-13. Ryan Tannehill finished 23-of-32 for 153 yards and an interception.
49ers at Titans Betting Analysis
On the San Francisco 49ers side
Wide receiver Deebo Samuel has been playing extremely well for the San Francisco 49ers this season as he has 61 receptions on 98 targets for 1,088 yards (17.8 yards per catch) with five receiving touchdowns and 39 rushing attempts for 269 yards (6.9 yards per carry) with seven rushing touchdowns.
In his last game against Atlanta, Samuel finished with four catches on five targets for 60 yards (15 yards per reception) as well as six carries for 29 yards (4.8 yards per rushing attempt) with a rushing touchdown.
The San Francisco 49ers have been a good defensive team this season as they are giving up 22.4 points per game. In their previous game against the Atlanta Falcons, San Francisco allowed 13 points on 275 total yards of offense (213 passing, 62 rushing).
The Falcons went 5-of-13 on third-down attempts and failed to convert on any of their three fourth-down opportunities. The Falcons allowed the 49ers to run the ball for 5.1 yards per carry.
On the Tennessee Titans side
The Tennessee Titans have been struggling without wide receiver Julio Jones being a factor as he has 25 receptions on 38 targets for 369 yards (14.8 yards per catch) without any touchdowns.
In his last game against Pittsburgh, Jones finished without a catch on one target before leaving the game with a hamstring injury.
The defense of the Tennessee Titans are doing a solid job this year as they are allowing 22.1 points per game. In their previous game against the Pittsburgh Steelers, Tennessee gave up 19 points on 168 total yards of offense (133 passing, 35 rushing).
The Steelers were not able to have big plays as they averaged just 3.7 yards per play and the Titans forced them to go just 1-of-3 inside of the red zone.
49ers at Titans Prediction
The San Francisco 49ers are currently listed as a 3.5 point road favorite in this game according to the top sportsbooks in the entire United States. The 49ers are scoring 28.8 points in their last five games, while the Titans are averaging 14.8 points in their previous four games.
The Titans are dealing with a lot of injuries to their skill position players as AJ Brown, Julio Jones, and Derrick Henry are all dealing with injuries.
This game is expected to be close but go with the San Francisco 49ers to cover the spread on the road here.
