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Home▷NFL Picks▷San Francisco 49ers vs. Los Angeles Rams Picks & Parlays

San Francisco 49ers vs. Los Angeles Rams Picks & Parlays

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Steph Chambers / GETTY IMAGES NORTH AMERICA / Getty Images via AFP

A pair of NFC West teams will square off at SoFi Stadium in Los Angeles on Sunday. The San Francisco 49ers and Los Angeles Rams won their Week 1 games. The 49ers could go to Pittsburgh and smack the Steelers around. The Rams also won on the road. Los Angeles went to Seattle and beat up the Seahawks. The winner of this game will take over first place alone in the NFC West.

It’s time to take a look at our 49ers vs Rams picks & parlays. Looking at the NFL team standings, we should be in for an exciting game.

San Francisco 49ers vs. Los Angeles Rams Odds

Before our 49ers vs Rams picks & parlays, let’s take a look at the NFL Point Spreads for the NFC West game on the Week 2 NFL schedule:

  • Spread: San Francisco 49ers -8, Los Angeles Rams +8
  • Total: 44.5
  • Moneyline: San Francisco 49ers -345, Los Angeles Rams +275

49ers vs. Rams Picks & Parlays

Matthew Stafford seems to be in control and poised. Look for him to be able to move the ball better than Pittsburgh did. The Rams also will get the run game going with Akers and Williams.

Look for both teams to get to 20+ in this game. This has the OVER written all over. The 49ers win, but the Rams cover. San Francisco 27-21 over the Rams on Sunday.

49ers vs. Rams Pick

  • Los Angeles Rams +8 against San Francisco 49ers

49ers vs. Rams Parlay

  • Los Angeles Rams +8
  • OVER 44.5
Top Sportsbook Bonus

San Francisco 49ers vs. Los Angeles Rams Information

San Francisco 49ers vs Los Angeles Rams

Date & Time: Sunday September 17th, 2023; 1:05pm PST

Location of the game: SoFi Stadium; Inglewood, CA

Where to Watch: FOX

In their previous matchup, the San Francisco 49ers smashed the Los Angeles Rams 31-14 back on October 30th, 2022.

San Francisco 49ers vs. Los Angeles Rams Betting Analysis

The 49ers sent Trey Lance to Dallas because they had so much confidence in Brock Purdy returning and doing what he did to finish last season. After his first start of 2023, that is a great idea.

Looking at the NFL team stats, Purdy was terrific for the 49ers, finishing with 220 passing yards and two touchdowns. Brandon Aiyuk was his target early and often in the game, finishing with eight receptions, 129 yards, and two touchdowns. His NFL MVP odds are slim.

Christian McCaffrey, at this point in his career, never surprises anyone with his final numbers. In a game that felt slow for the running back, he got 22 carries and finished with 152 yards and a touchdown. On the defensive end, the 49ers caused Kenny Pickett to throw two interceptions, and they held Najee Harris to just 31 rushing yards in his NFL Player Stats. Anytime you get a San Francisco 49ers game, you never know what offensive weapon will come through.

For the Rams, Sean McVay needed the offseason to regroup and prepare for the 2023 season. This will be a challenging season for McVay with so many new faces in the lineup. Week One was positive, with a masterful game plan and a big win over Pete Carroll and the Seattle Seahawks.

Cam Akers and Kyren Williams got a bunch of carries for the Rams, with Williams finishing with 52 yards and two touchdowns. TuTu Atwell was the top receiver, as he went over 100 yards on six receptions. Matthew Stafford finished the game with 334 passing yards, which was second most in all of Week 1. The Los Angeles Rams schedule in Week 3 sends them to Cincinnati to take on the Bengals.

San Francisco 49ers vs. Los Angeles Rams Betting Picks

Heading back with our picks for this game. Barring any late additions to the NFL injury report, this will be a fun one. The 49ers are one of the most talented teams in the league.

Brock Purdy has been outstanding. Matthew Stafford will have his work cut out to stay competitive in this game. But look for him and McVay to carry through a good game plan and stay close.

Our final betting picks for our 49ers vs Rams picks & parlays on Sunday are the Los Angeles Rams +8 and the OVER 44.5! Hope you enjoy all our NFL Picks against the Spreads for the big NFL Matchups this week!

If you love sports and want more sports betting information follow us as @InsidersBetDig on Twitter and sign up to our mailing list for free betting picks.

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