Buffalo Bills vs Chicago Bears

In NFL Week 16 of the NFL schedule, the Buffalo Bills and Chicago Bears will face off in an inter-conference matchup at Soldier Field. With both of these teams playing in areas where the weather gets cold, the conditions in Chicago could play a very interesting role in determining how this contest plays out. In our Bills vs Bears betting analysis, we look at the stats and trends that bettors need to know about before wagering on this showdown in the Windy City.

Rivalry History

There is not a lot of data to go off of when it comes to the Bears and Bills, which means that previous matchups will not have any sort of impact on Bills vs Bears odds. These teams have played 13 NFL matchups all-time heading into this contest, with the Bears winning eight of those 13 games. Chicago won the last meeting between these teams, beating the Buffalo Bills by a score of 41-9 in Buffalo before Josh Allen took over as Bills quarterback.

With these teams playing in different conferences, they play each other once every four seasons. Therefore, both rosters have undergone some serious changes since the last time they have met. Not only was Josh Allen not in the league the last time these teams met, but Justin Fields was also not in the league yet before he was drafted by the Chicago Bears ahead of the 2021 season.

Matchup Trends

Before betting on Bills vs Bears, it is a good plan to check out the NFL stats for both of these teams before locking in any bets. Buffalo has been one of the best NFL teams on defense over the last couple of years, but any changes to that status could open the door for an upset win for the Bears. It is vital to get the latest statistical information before betting on this contest so as not to miss any data that could inform betting decisions one way or the other when Buffalo and Chicago square off.

Venue Information

The Chicago Bears will host this game at Soldier Field in Chicago, which is one of the most legendary venues in the NFL. But even when playing at a historic venue, the Bears have not been able to use their home field advantage to finish high in the NFL standings in recent seasons. Chicago has not finished a season with a winning record at home since the 2018 season, though they are looking to change that in 2022.

Buffalo, meanwhile, has become one of the better NFL teams at winning games on the road. They have had three straight winning seasons on the road going into 2022, and even kicked off their 2022 campaign with a road win against the Los Angeles Rams. With such an explosive offense, the Bills have been able to win no matter where they have been.

Betting Tips for Buffalo Bills vs. Chicago Bears

Any Bills vs Bears betting analysis would likely agree that the NFL odds for this contest should favor the Bills. However, those making NFL picks against the spread should keep an eye on a number of factors before assuming the result of this contest is a foregone conclusion. NFL Injuries will be especially important to monitor late in the season, as the physical challenges of a full NFL season could hamper even the best teams in the league.