San Francisco 49ers vs Atlanta Falcons

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49ers vs. Falcons Odds and Betting Analysis

The Atlanta Falcons host the San Francisco 49ers in Week 6 of the NFL season. This game looks like a mismatch on paper, but things can change once the season begins.

49ers vs. Falcons Betting Preview

Some NFL matchups stand out yearly, but that won’t be the case when the Atlanta Falcons host the San Francisco 49ers. These two NFL teams are expected to have very different seasons in 2022, but things can always change once the games begin.

San Francisco made it to the NFC Championship Game a season ago, and they are expected to be just as good this season. The 49ers are making a change at the quarterback position, which could present some challenges early on.

The NFL stats for the Atlanta Falcons in 2021 were pretty poor to look at, and it’s expected to be another long season. Atlanta is in the middle of a long rebuild, and it’s going to be a difficult season in 2022. 

This 49ers vs. Falcons betting analysis will include some of the better ways to look at this matchup. 

Rivalry History

Since the 49ers and Falcons are not in the same division in the NFC, then they aren’t often playing against each other on the NFL schedule. San Francisco holds a 48-32-1 advantage over Atlanta in the all-time series, but things have been pretty even over the past five matchups.

Matchup Trends

The 49ers vs. Falcons betting analysis shows these two NFL teams actually played during the 2021 regular season, and that game could give you some input as to how this game will play out. San Francisco came away with a dominant 31-13 victory last season, and it could be even worse for the Falcons in this one.

Atlanta no longer has quarterback Matt Ryan leading the way, and that defense is going to struggle again. Even though the 49ers are going to be making a change at quarterback, the rest of the roster remains intact. 

Venue Information

The game’s venue can influence bettors when making NFL picks, and Atlanta usually has a good home-field advantage. Mercedes-Benz Stadium is the home of the Atlanta Falcons, and it should be a packed house ready to cheer on the home team. 

Betting Tips for 49ers vs. Falcons

You will want to wait until the end of Week 5 to find the best 49ers vs. Falcons betting odds for this matchup. The NFL standings through the first five weeks will give you a better idea of how these teams match up heading into this game. 

It is supposed to be a long year for the Atlanta Falcons, but they could always come out and surprise some people in 2022. San Francisco has a good roster to win the Super Bowl, but they will also need some things to go well. 

Wait for the NFL odds to be released after Week 5 before you make a bet on this matchup. Keep this in mind if you are learning how to bet on football.

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