We have reached the final week of Spring Training action around MLB as the regular season starts this week. The Seattle Mariners visit the San Diego Padres on Monday night for a chance to prepare for the season opener.
Mariners vs Padres Picks

- Pick 1: San Diego Padres -1.5
- Pick 2: Over 8.5 Runs
This should be one of the top games on the MLB schedule today, and lead to some great betting opportunities. Here are some Mariners vs Padres best predictions that should be made after looking at the scores and odds.
Seattle Mariners vs San Diego Padres Odds
Seattle Mariners vs San Diego Padres Matchup Information
Mariners vs Padres
Location of the Game: Petco Park, San Diego, California
Date & Time: Monday, March 25, 9:40 PM ET
How to Watch: MLB Network
Recent Scores for Last Game
Looking at the recent scores for each team can help when making Mariners vs Padres best predictions on Monday night. Seattle has gone 3-0-2 in their last five, and they are now at 13-13 so far in Cactus League.
The San Diego Padres already played perhaps the best team in the MLB in a two-game series in South Korea. San Diego went 1-1 against the Dodgers, and they are back home to tune up for more regular-season action.
Seattle Mariners vs San Diego Padres Analysis
To find the MLB best bets that we can make on Monday night, you will need to look at how each team has been playing. Seattle did just score nine runs in their most recent game, but they also gave up nine runs.
The Mariners have pitched to a team ERA of 5.83 so far in Spring Training, and that has been a serious issue for this team. San Diego has also struggled to get outs over the last few weeks, and that includes the two regular season games against the Dodgers.
Jake Cronenworth belted a home run in that series in South Korea, and Manny Machado had a big series as well. This Padres team is absolutely loaded with talent, and they are a tough team to deal with.
Odds Breakdown
When trying to find the Mariners vs Padres best predictions on Monday night, checking out the MLB betting odds is going to be extremely important. Betting the over/under is always an option when making MLB picks and parlays and that line is set at 8.5 total runs.
Seattle Mariners
Even though the Seattle Mariners have been playing well of late, they are moneyline underdogs in this game at +100 in the BetUS lines. Seattle is getting 1.5 runs on the run line, and that is another option to check out.
San Diego Padres
When looking at some Mariners vs Padres best bets in this game, the moneyline is set at -130 in favor of San Diego. Taking the San Diego Padres at -1.5 is going to provide even more betting value.
Seattle Mariners vs San Diego Padres Betting Pick and Prediction
After looking at some Mariners vs Padres betting analysis for this matchup on Monday night, there are two bets that stand out. This has the potential to be one of the top MLB games today, but the Padres just have too much in-game experience.
Seattle has been playing very well of late, but they are going to be facing a tough environment. The Mariners just won’t be able to slow down the Padres explosive lineup.
Taking the Padres at -1.5 is one of the best bets to, and that should also go with over 8.5.
- Pick 1: San Diego Padres -1.5
- Pick 2: Over 8.5 Runs
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