It’s the Virginia Cavaliers and the Louisville Cardinals in College Football action on Thursday. The Virginia Cavaliers come into the game looking to pull a massive weeknight upset. Virginia is 2-7 on the season, and coming off a blowout loss at home to Georgia Tech. The Cavaliers have lost their last two games.
Virginia vs. Louisville Picks

Louisville Cardinals -20 over the Virginia Cavaliers
For Louisville, they are 8-1 on the season, and have won back-to-back games. The Cardinals beat up on Virginia Tech 34-3 on Saturday. Let’s get to our Virginia vs Louisville betting picks:
Virginia Cavaliers vs. Louisville Cardinals Odds
Let’s take a look at the latest NCAAF odds for these two NCAA Football teams:
ACC Showdown: Virginia vs. Louisville
Before our Virginia vs Louisville betting picks, some information on both of these NCAA Football teams:
Virginia Cavaliers vs Louisville Cardinals
Location of the game: L&N Federal Credit Union Stadium. Louisville, KY.
Date & Time: Thursday, November 9. 7:30 pm EST.
How to watch: ESPN
Virginia Cavaliers vs. Louisville Cardinals Analysis
It’s been a tough and frustrating season for the Virginia Cavaliers in 2023. In the loss on Saturday, the Cavaliers saw Georgia Tech’s Haynes King dominate them with two rushing and three passing touchdowns. The loss was their second straight, and officially eliminated them from a bowl game. The Virginia Cavaliers football stats for 2023 have been pretty ugly.
The two wins for the Cavaliers came back to back. They were able to beat William and Mary at home, and then went on the road and upset North Carolina. The Cavaliers are allowing teas to score 32.4 points per game against them. On the offensive side, Virginia is scoring just 23.1 points per game.
The Cavaliers have one of the worst run offenses in all of College Football. Virginia is picking up just 120.2 yards per game on the ground. After this game, they will have no more road games this season. First, the Duke Blue Devils come to town, and then the season finale is at home against Virginia Tech.
Louisville’s ACC Title Hopes Remain Alive
For Louisville, an Atlantic Coast Conference title is still in play. The Cardinals have just one loss, and that was to Georgia Tech. They are the only team with just a single conference loss, while Florida State is unbeaten. The Cardinals finish the season at Miami, and then a non conference game against the Kentucky Wildcats. With a win in this game, and a win over Miami, the Louisville Cardinals standings in conference play will get them to the title game.
Louisville is led by quarterback Jack Plummer, running back Jawhar Jordan and receiver Jamari Thrash. Plummer is over 2,100 yards passing, with 14 touchdowns on the season. Thrash is the top receiver on the team with 712 receiving yards and six touchdowns, while Jordan needs just 119 more yards on the ground to get to 1,000.
The Cardinals are scoring 32.9 points per game, and have one of the best team defenses in all of College Football, allowing just 16.3 points per game.
Virginia vs. Louisville Betting Picks
These are our Virginia vs Louisville betting picks: This is not going to be a pretty football game for the Virginia Cavaliers. Look for the Cardinals to be able to mix it up with the pass and the run, while Virginia is thrown off, and cannot defend either one.
On the other side, Virginia simply struggles to move the ball, and the Louisville defense holds them to just two field goals in this game. The betting pick for this Thursday evening game is the Louisville Cardinals -20 over the Virginia Cavaliers.
Virginia Cavaliers vs. Louisville Cardinals Prediction
Our final score prediction is the Louisville Cardinals 35-6 over the Virginia Cavaliers. For Louisville, Jordan goes over 100 yards on the ground, and reaches 1,000 on the season. Take the Cardinals at home in an Atlantic Coast Conference game Thursday night!
Good luck with all your College Football predictions on the NCAAF schedule!
- NCAAF Pick: Louisville Cardinals -20 over the Virginia Cavaliers
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