Monday Night Football for Week 7 will feature the San Francisco 49ers at the Minnesota Vikings. San Francisco comes into the game as leaders of the NFC West. The 49ers are 5-1. After winning their first five games, the 49ers are coming off a loss on the road at the Cleveland Browns in Week 6. For Minnesota, they are 2-4.
49ers vs Vikings Picks

- NFL Pick: Bet San Francisco -6.5
The Vikings are third in the NFL Standings for the NFC North behind the Lions and Packers. Minnesota is coming off a win on the road at the Bears last week. Let’s get to our 49ers vs. Vikings Betting Analysis:
San Francisco 49ers vs. Minnesota Vikings Odds
49ers vs. Vikings Information
One of the most intriguing NFL Matchups of the week here. Here is some information on the Monday Night Football game on the NFL Schedule:
San Francisco 49ers vs Minnesota Vikings
Location of the game: US Bank Stadium. Minneapolis, MN.
Date & Time: Monday, October 23. 7:15 pm CST.
How to watch: ABC | ESPN
Recent Scores
Here are some San Francisco 49ers score results:
San Francisco 49ers 2023 Results
- Sunday, October 1st, 2023: 35-16 win over Arizona Cardinals
- Sunday, October 8th, 2023: 42-10 win over Dallas Cowboys
- Sunday, October 15th, 2023: 19-17 loss at Cleveland Browns
And like you can see, the Minnesota Vikings schedule with results:
Minnesota Vikings 2023 Results
- Sunday, October 1st, 2023: 21-13 win over Carolina Panthers
- Sunday, October 8th, 2023: 27-20 loss vs. Kansas City Chiefs
- Sunday, October 15th, 2023: 19-13 win at Chicago Bears
San Francisco 49ers vs. Minnesota Vikings Betting Analysis
Here are the latest NFL Odds for our 49ers vs. Vikings Betting Analysis:
- Spread: San Francisco 49ers -6.5, Minnesota Vikings +6.5
- Moneyline: San Francisco 49ers -300, Minnesota Vikings +250
- Total: 43.5
49ers vs. Vikings Betting Preview
Minnesota has a chance to really get back into things if they can win on Monday Night Football here. The Vikings are 2-4 and have a couple of winnable games upcoming. Minnesota, though will have to do so without their top receiver Justin Jefferson, who is on the NFL Injury List for at least three more games. Jefferson leads the team with 571 receiving yards.
Minnesota is going to need to figure out their run game. Alexander Mattison remains the top running back, with 320 yards, but Cam Akers is now also getting involved. Minnesota ranks 30th in all of the league with just 75 yards per game. That puts a ton of pressure on Kirk Cousins and his arm, which is leading Minnesota to third in the league with 275 yards per game.
The Vikings will play back-to-back road games and three of their next four on the road. Those games are at the Packers, at the Falcons, and then at the Broncos, following a home game against the Saints. After that, Minnesota gets the Bears again on Thanksgiving weekend.
49ers’ Defensive Dominance
Speaking of the best offensive players missing the game, Christian McCaffrey of the 49ers may miss this game. He left the loss to the Browns with an oblique injury and did not return. That would be a massive loss for the 49ers, as his NFL Player Stats have him with 110 carries for 553 yards and 7 touchdowns.
Brock Purdy had his worst game of the season against the Browns. Now, Purdy has 1,396 yards passing, 10 touchdowns and an interception. Brandon Aiyuk is the top threat for the 49ers so far this season, with 2 touchdowns. The 49ers rank as the best defensive team in the league according to NFL Team Stats, allowing just 14.5 points per game.
The 49ers go home after this game and take on the Cincinnati Bengals before their bye week.
San Francisco 49ers vs. Minnesota Vikings Betting Prediction
We expect a really good game here, but in the end, the 49ers are the better team. The 49ers will struggle with really tough, defensive teams. That is not Minnesota. Look for McCaffrey to play, and the 49ers to win by 10. Bet San Francisco -6.5.
That is our final 49ers vs Vikings Betting Analysis. Hope you enjoy all our NFL Picks!
- NFL Pick: Bet San Francisco -6.5
Discover the latest stats and trends of this matchup here:
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