The Buffalo Bills are on the road at the Kansas CIty Chiefs in a huge AFC showdown on Sunday. This is part of the Week 14 slate in the National Football League. The Buffalo Bills are coming off their bye week. Before the bye, the Bills lost on the road at the Philadelphia Eagles. Buffalo is 6-6, and second in the AFC East, but currently out of the postseason picture.
Bills vs Chiefs Picks

Pick: Bills ML (+100)
For Kansas City, they are 8-4 on the season. The Chiefs are coming off a loss on the road at Green Bay on Sunday. Kansas City leads the AFC West, and is tied for third in the AFC standings. The Buffalo Bills beat the Kansas City Chiefs on October 16th, 2022. Let’s get to our Bills vs Chiefs betting picks:
Buffalo Bills vs. Kansas City Chiefs Odds
Here are the updated NFL Odds, to help make the best NFL Picks for this game:
- Spread: Kansas City Chiefs -1.5, Buffalo Bills +1.5
- Total: 48.5
- Moneyline: Kansas City Chiefs -120, Buffalo Bills +100
Buffalo Bills vs. Kansas City Chiefs Information
Before our Bills vs Chiefs betting picks, some information on one of the best NFL Matchups of the week:
Buffalo Bills vs Kansas City Chiefs
Date & Time: Sunday December 10th, 2023; 3:25 pm CST
Location of the game: Arrowhead Stadium; Kansas City, MO
How to Watch: CBS
Matchup Analysis
The Buffalo Bills are hoping to put the overtime loss against the Eagles behind them. They will have to as they are in a big spot on the road. On the season, Buffalo has been pretty strong offensively. The Bills are throwing for more than 260 yards per game, which is 5th in the league. Buffalo is scoring 27.3 points per game, also fifth in the league.
Josh Allen has got to take care of the football more. But, his numbers are not that bad. He is completing more than 68% of his passes, and has 24 touchdowns on the season. The 13 interceptions is the number many are looking at.
The Bills schedule does not get easier next week, as they host Dallas. After that, they are at the Chargers, with the Patriots, and then on the road at the Miami Dolphins.
Patrick Mahomes will come into this game against the Bills throwing 444 passes on the season. He has completed 301 of them, for nearly 68%. Mahomes has 22 touchdowns on the season, with 10 interceptions. His top target, Travis Kelce has seen 93 targets, for 74 receptions and 813 yards on the season.
Isaiah Pacheco is questionable for this game with a shoulder injury. He has been the best running back for Kansas City. The former Rutgers star is 221 yards shy of 1,000 on the season, with six touchdowns.
The Chiefs are on the road at New England next week, before hosting the Raiders and Bengals. Kansas City finishes on the road at the Chargers.
Buffalo Bills vs. Kansas City Chiefs Betting Pick
The Kansas City Chiefs just seem to have something a little off with them. But, in saying that, the Buffalo Bills have been dreadful for many games this season. Dreadful in the way they finish games. That is going to change here. The Buffalo Bills know their backs are against the wall. They need a win, and they need it badly. It would be a massive jumpstart for the Bills in their final four games if they could grab this one.
We are betting the Bills to win this game straight up. Our final bet is the Buffalo Bills +100 over the Kansas City Chiefs in the scores and odds.
- Pick: Bills ML (+100)
Buffalo Bills vs. Kansas City Chiefs Prediction
The Kansas City Chiefs just cannot seem to put it all together. They cannot run the football when their receivers are catching passes. They cannot catch passes when the running backs are getting yards.
The defense has been good, but does not always get the stop they need. Andy Reid has some work to do before the postseason. The final score prediction here is the Buffalo Bills 28-21 over the Kansas City Chiefs on Sunday! Hope you enjoyed our Bills vs Chiefs betting picks!
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