The Houston Astros (2-1) will look to close the American League Division Series against the Minnesota Twins (1-2) on Wednesday. For the Twins, they are hoping to force a decisive Game 5 with a win in this one.
After splitting the first two games of the series, the Astros were able to dominate the Twins Tuesday to the tune of a 9-1 win. In the victory, Christian Javier picked up the win while Jose Abreu hit two home runs and drove in five.
Astros vs Twins Picks

Bet on the Astros to win the game (ML +110) and the game total to hit the over
For Minnesota, they were only able to manage three hits in the contest. Sonny Gray took the loss after allowing five runs (four earned) over four innings of work.
While both of these teams finished atop the MLB standings in their respective divisions, it is the Astros that are just one game away from moving on to the ALCS.
Heading into this matchup, let’s take a look at our Astros vs Twins picks & parlays.
Houston Astros vs. Minnesota Twins Odds
Before determining our Astros vs Twins picks & parlays, it is important to analyze the MLB odds.
- Moneyline: The Twins come into this one as slight favorites playing at home. They are -120 to win, while the Astros’ moneyline sits at +110.
- Spread: The spread features Houston at +1.5, with odds of -190. The spread for the Twins sits at -1.5, with odds of +160.
- Over/Under: In terms of the total runs, the over/under is set at eight. The over eight runs has odds of -115, while the under has odds of -105.
Houston Astros vs. Minnesota Twins Picks & Parlays
The Houston Astros showed Tuesday that they have been a far superior team this season when playing on the road. Expect that trend to continue on Wednesday.
Houston Astros vs. Minnesota Twins Pick:
- Houston Astros to win straight up on the road (+110) against the Minnesota Twins.
Houston Astros vs. Minnesota Twins Parlay:
- Astros To Win (+110)
- Over on total runs (-115)
Astros vs. Twins Information
Houston Astros vs Minnesota Twins
Location of the game: Target Field, Minneapolis, Minnesota
Date & Time: October 11, 2023, 7:07 pm ET
Where to Watch: National – FS1, FS1-INT
Houston Astros vs. Minnesota Twins Betting Analysis
For the Houston Astros game today, manager Dusty Baker will hand the ball to 28-year-old righty Jose Urquidy. Looking at his MLB player stats, he has pitched in 12 career postseason games, going 3-2 with a 3.72 ERA and 1.24 WHIP, and he has 36 strikeouts in 36.1 innings. In his last start, stemming back to the regular season, Urquidy was dominant in a win over the Arizona Diamondbacks. In that victory, he went six shutout innings, allowing just two hits and struck out two.
The Astros currently rank fifth out of all MLB teams in scoring, averaging 5.09 runs per game. They are even better on the road, averaging 5.70 runs.
Yordan Alvarez has been the Astros’ best hitter this postseason. In just 12 at bats, he is hitting .500/.538/1.667 with four home runs and six runs batted in.
As for the Twins, they will turn to 27-year-old righty Joe Ryan on Wednesday. In 29 MLB games this season, he went 11-10 with a 4.51 ERA and 1.17 WHIP, and he had 197 strikeouts in 161.2 innings.
His last start, back on September 29, was a rough one as he gave up six earned runs over five innings to the Colorado Rockies. In fact, in his last three starts, he has given up 13 earned runs in 16 innings of work.
Offensively, the Twins rank 10th in the majors in scoring, averaging 4.78 runs per game. Royce Lewis leads the team this postseason with three home runs, four runs batted in, and five runs scored.
As for the MLB injury report, Houston is without pitchers Lance McCullers Jr (forearm) and Luis Garcia (forearm). As for the Twins, they will be without outfielders Byron Buxton (hamstring) and Joey Gallo (foot).
Houston Astros vs. Minnesota Twins Betting Picks
Houston comes into this one not only with the confidence of having a lead in the series but also with the experience of having been in this position before. As defending champions, they will look to use that experience to close out the series on Wednesday.
Looking at the trends, the Astros are 10-5 in their last 15 games against the Twins. Houston is also undefeated in their last five road games overall.
As for the Twins, they are just 3-9 in their last 12 home games against the Astros. For that reason, take the Astros as underdogs to win on the road.
Also, with two top-10 offenses on the field, don’t be surprised if both offenses are at least able to find a little success.
- As far as our Astros vs Twins picks & parlays, take the Astros to win (+110) and the over to hit on total runs (-115).
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