In Week 10, the Monday Night Football showdown unfolds at Highmark Stadium in Orchard Park, New York, showcasing a clash between the Denver Broncos and the Buffalo Bills. These two teams haven’t faced off since December 19th, 2020, when the Bills dominated the Broncos with a commanding 48-19 victory.
Broncos vs Bills Picks

- NFL Pick: Buffalo -7.5 over Denver
Fresh from a bye week, the Denver Broncos are riding the momentum of a significant upset against the Kansas City Chiefs. Despite this triumph, their overall season record stands at 3-5, placing them at the bottom of the AFC West standings.
Meanwhile, the Buffalo Bills have faced challenges throughout the season, currently holding a 5-4 record and falling short of preseason Super Bowl expectations. Despite their struggles, a silver lining exists, as a Week 9 loss for the Dolphins keeps the Bills just one game behind in the division, with a previous head-to-head victory over Miami.
Buffalo’s previous week saw them succumb to the Bengals with a 24-18 defeat. Entering this matchup, the Buffalo Bills are heavily favored with a -7.5 spread over the Denver Broncos. The game’s total points are set at 46.5, creating an intriguing dynamic for Monday night’s football spectacle. Let’s get to our Broncos vs Bills betting analysis:
Denver Broncos vs. Buffalo Bills Information Odds
Broncos vs. Bills Information
Before the Broncos vs Bills betting analysis, take a look at some information on both teams in one of the NFL Matchups for Week 10:
Denver Broncos vs Buffalo Bills
Location of the game: Highmark Stadium. Orchard Park, NY.
Date & Time: Monday, November 13. 8:15 pm EST.
How to watch: ESPN
Recent Scores
Denver Broncos Last 3
- Sunday, October 15th, 2023: 19-8 loss at Kansas City Chiefs
- Sunday, October 22nd, 2023: 19-17 win over Green Bay Packers
- Sunday, October 29th, 2023: 24-9 win over Kansas City Chiefs
Buffalo Bills Last 3
- Sunday, October 22nd, 2023: 29-25 loss at New England Patriots
- Thursday, October 26th, 2023: 24-18 win over Tampa Bay Buccaneers
- Sunday, November 5th, 2023: 24-18 loss at Cincinnati Bengals
Denver Broncos vs. Buffalo Bills Betting Analysis
Take a look at the Buffalo Bills odds as they take on the Denver Broncos in this game on the NFL schedule.
- Spread: Buffalo Bills -7.5, Denver Broncos +7.5
- Total: 46.5
- Moneyline: Buffalo Bills -380, Denver Broncos +300
Denver Broncos vs. Buffalo Bills Betting Preview
The Buffalo Bills are showcasing offensive prowess this season, ranking second in the AFC and third in the National Football League with an impressive 240 points scored.
Quarterback Josh Allen has been a key architect of this success, amassing over 2,400 passing yards and 18 touchdowns, while star receiver Stefon Diggs is on the brink of reaching 1,000 receiving yards, needing just 166 more. Diggs also leads the team with 7 touchdowns. However, the Bills face challenges in their run game, averaging a modest 108.1 yards per game over nine matchups.
Defensively, the Bills have held their ground, conceding 160 points, a commendable feat compared to counterparts like the Kansas City Chiefs, who allowed 143 points in the same span. Despite these individual achievements, the Bills struggle to put together their solid performance, evident in losses to the Jets, Jaguars, Patriots, and Bengals, each revealing distinct issues at different junctures. Finding a connection remains the key for the Bills as they navigate the complexities of their season.
Broncos’ Remarkable Turnaround
The Denver Broncos aim to extend their winning streak to three games, marking a remarkable turnaround from a rocky start that saw them concede 122 points in the initial three matches. Recent defensive prowess is evident, with only 26 points allowed in the last two games, propelling the Broncos to 31st in the league, permitting an average of 28.3 points per game.
Quarterback Russell Wilson faces scrutiny amid a season where he’s amassed 1,613 yards and 16 touchdowns, relying heavily on top receiver Cortland Sutton, who has yet to surpass 400 yards in 2023.
When looking at Denver Broncos player stats – Javonte Williams leads the ground game, setting the stage for consecutive home games, including a Sunday Night Football clash against Minnesota and hosting the Browns post-Thanksgiving. Denver seeks to solidify their resurgence and maintain momentum in the upcoming matchups.
Denver Broncos vs. Buffalo Bills Betting Prediction
Here is our final Broncos vs Bills betting analysis – this prediction goes to Buffalo. The Bills are better than the Broncos. Denver has been playing better football as of late, but the Bills at home are too much. Take Buffalo -7.5 over Denver!
- NFL Pick: Buffalo -7.5 over Denver
Discover the latest stats and trends of this NFL matchup here:
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