The Buffalo Bills and Indianapolis Colts will square off on Saturday in a preseason tilt. The Buffalo Bills went 13-3 a season ago and came away with the second seed in the AFC East.
The Bills won the division by four games over Miami after winning their final seven games of the season. Buffalo went 7-1 in home games. For the Indianapolis Colts, it was a season to forget.
The Colts went 4-12-1 a season ago and lost their last seven games. The Colts finished ahead of only Houston in the NFL standings AFC South. Here are some of our Colts vs Bills Best Bets.
If we take a quick look at the NFL schedule, this should be one of the better NFL matchups this week!
Indianapolis Colts vs. Buffalo Bills Odds
Indianapolis Colts vs. Buffalo Bills Information
Before we give you our Colts vs Bills Best Bets, here is some updated information on the game:
Indianapolis Colts vs Buffalo Bills
Location of the game: Highmark Stadium, Orchard Park, NY.
Date & Time: Saturday, August 12. 1:00 pm ET.
How to watch: NFL Season Pass
Recent Scores
These two teams have not played since 2021. The Indianapolis Colts smacked the Buffalo Bills 41-15 back on November 21st, 2021.
Indianapolis Colts vs. Buffalo Bills Analysis
Indianapolis Colts
Looking at the recent NFL team stats, it is obvious that it has not been the best off-season for the Indianapolis Colts. The Jonathan Taylor drama has been ongoing, and there is no end in sight when the star running back looks like he may join the team.
Without Taylor, the Colts will turn to Deon Jackson and Kenyan Drake, both veterans in the league; there is a good chance Indianapolis will be looking to add to the NFL roster in the next few weeks.
The Colts are planning to go with Gardner Minshew as the starting quarterback. He will play in front of Anthony Richardson, who they drafted out of Florida, and also youngster Sam Ehlinger. Last season, the quarterback play of the Colts was horrific.
Colts’ Supporting Cast
Indianapolis saw Matt Ryan, Sam Ehlinger, and Nick Foles combine for just 17 touchdowns and 20 interceptions. It was ugly numbers when looking at the Indianapolis Colts Stats.
The Colts will still turn to Michael Pittman as the top receiver. The quarterbacks are going to want to get him the ball as the top playmaker on the squad. Other guys with chances to shine include Alec Pierce, Isaiah McKenzie, Ashton Dulin, and Breshard Perriman.
The Colts will likely use a wide array of guys in this first preseason affair. Indianapolis starts their 2023 regular season on September 10th at home against divisional favorite Jacksonville.
Buffalo Bills
High hopes remain in Buffalo, where the Bills look to add their name to the list of AFC teams heading to the Super Bowl. While Kansas City has had its share, and Cincinnati got theirs, Josh Allen and company are ready to make sure it’s their time.
The Buffalo Bills schedule sees them at New York Jets on Monday Night Football to start the season. After that, the Bills have a pair of winnable games at home against the Raiders and on the road at the Commanders.
Allen will not play in this game, but Buffalo will get looks at guys like Kyle Allen and Matt Barkley at backup. James Cook is projected to be the starting running back, while guys like Damien Harris, Latavius Murray, and Darrynton Evans await their chance.
Buffalo’s Aerial Ambitions
Looking at the past NFL player stats, Stefon Diggs and Gabe Davis are a heck of a 1-2 punch in the receiving core. The Bills will look to see if they can add a third name to that as a reliable core. Khalil Shakir gets the first chance, but guys like Trent Sherfield, Deonte Harty, and Justin Shorter will make their case.
The Bills, a season ago, got a ton of Allen. Allen threw for 4,283 yards and 35 touchdowns. He was also the second-leading rusher with more than 760 yards on the ground and seven touchdowns.
Gone is Devin Singletary, so it will be interesting to see how the offense adjusts with new blood in the backfield.
Odds Breakdown for Indianapolis Colts vs. Buffalo Bills
It is important to take a quick look at the NFL odds before making any betting picks!
- Moneyline: Indianapolis Colts -205 | Buffalo Bills +170
- Spread: Indianapolis Colts -5.5 | Buffalo Bills +5.5
- Total: 39
Indianapolis Colts vs. Buffalo Bills Betting Pick and Prediction
It’s the preseason, but it’s surprising to see the Colts as this big of a favorite. This game is going to be much closer than that. Despite the Bills playing back-ups, they still will have a talented bunch out there.
Barring any late additions to the NFL injury report, these are the Colts vs Bills Best Bets:
- Buffalo Bills +170
- Buffalo Bills +5.5
- Under 39
As for the final prediction of our NFL picks, go with the Buffalo Bills to win this game 20-17 over the Indianapolis Colts. Obviously, when the games don’t count, the stakes are not as high, but we like the Bills’ chances here.
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