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Home▷NFL Picks▷San Francisco 49ers vs Los Angeles Rams Betting Picks and Prediction

San Francisco 49ers vs Los Angeles Rams Betting Picks and Prediction

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Ezra Shaw/Getty Images/AFP

It’s NFL week 8 of the season, and the San Francisco 49ers travel to Los Angeles to play the Rams this weekend in an important NFC West matchup.

San Francisco won 24-9 against the Rams earlier this season. Before making a single 49ers vs Rams prediction, here is an analysis of each team’s season so far.

San Francisco 49ers vs. Los Angeles Rams

Matchup Info

  • Game Day: Sunday, October 30, 2022
  • Game Time: 4:25 PM ET
  • TV Channel: FOX
  • Location: Inglewood, California
  • Stadium: SoFi Stadium

San Francisco 49ers

Entering this weekend’s game, the 49ers are 3-4 this season. San Francisco has lost two games in a row ahead of this weekend’s game.

The 49ers lost 44-23 to the Kansas City Chiefs last weekend, having lost 28-14 to the Falcons the previous weekend.

Before their back-to-back losses, San Francisco had previously won back-to-back games, including a 24-9 win against the Rams during the two teams’ first matchup of the season.

49rs Averaging Numbers

During that game, the 49ers’ defense allowed only 257 yards, including only 57 rushing yards. The 49ers’ odds of making the playoffs are still solid.

They enter this weekend’s game in third place in the division but would improve to second place if they won. The Seattle Seahawks currently lead the NFC West with a 4-3 record.

Garroppolo Stats

In the team’s first game against the Rams earlier this season, Jimmy Garroppolo completed 16 of 27 passes for 239 passing yards and one touchdown.

Overall, Garroppolo has completed 64.3% of his passes for 1,456 passing yards, nine touchdowns, and four interceptions.

McCaffrey’s Trade

Since winning their first game against Los Angeles a few weeks ago, San Francisco has completed a trade for Christian McCaffrey, who had eight carries for 38 yards last weekend.

The 49ers will hope that the addition of McCaffrey to the running game helps them beat the Rams for the second time this season.

Key Injuries

  • WR Deebo Samuel (Hamstring) – Questionable
  • CB Jason Verrett (Knee) – Questionable
  • DE Arik Armstead (Foot) – Questionable
  • DE Samson Ebukam (Achilles) – Questionable
  • LB Dre Greenlaw (Calf) – Questionable
  • WR Jauan Jennings (Hamstring) – Questionable
  • FB Kyle Juszczyk (Hand) – Doubtful

49ers Betting Trends to Know

San Francisco is 3-4 against the spread after the first seven games of their NFL schedule.

In two of the team’s last three games, there have been more total points than the over/under.

Los Angeles Rams

The Rams won 24-10 against the Carolina Panthers in their last game, and the team did not play last weekend. The Rams have also won against the Falcons and Cardinals this season but have lost games against the Cowboys and the 49ers.

Rams’ Scoring Points

The Rams’ stats show that they score 17.3 points per game, currently the 29th-best in the NFL. This is in contrast to last season when Los Angeles scored 27 points per game, which was the sixth-best in the league.

Last weekend, Matthew Stafford completed 26 of 33 passes for 253 passing yards, one touchdown, and one interception.

He has completed 71.1% of his passes this year, an improvement from 67.2% last year, but he is averaging 262.7 passing yards per game this season after averaging 287.4 yards last season.

Rams’ Defense

So far this season, the Rams’ defense is allowing 21 points per game, which is currently 16th in the NFL, which could have an impact on any 49ers vs Rams prediction.

Last season, Los Angeles’ defense allowed 21.3 points per game. This weekend’s game will significantly impact which team wins the NFC West division.

Ahead of the game, here is a look at the Rams’ NFL injury report for this weekend.

Key Injuries

  • RB Darrell Henderson, Jr. (Illness) – Questionable
  • RB Cam Akers (Personal) – Doubtful
  • S Quentin Lake (Knee) – Out

Rams Betting Trends to Know

The under is 5-1 in Rams games so far this season, which could affect the 49ers vs Rams prediction. The Rams are 2-4 against the spread so far this season.

San Francisco 49ers vs. Los Angeles Rams Odds

Ahead of making NFL picks week 8, the 49ers’ moneyline for this weekend’s game is -125, while the Rams’ is +105.

San Francisco enters this weekend’s game as a 1.5-point favorite despite playing on the road. The over/under for Sunday’s game is 43.

San Francisco 49ers vs Los Angeles Rams Betting Picks

Moneyline

The San Francisco 49ers won these two teams’ first matchup earlier this season, and McCaffrey should help the team’s offense improve. San Francisco should improve to 4-4 on Sunday.

NFL Pick: 49rs (-120)

Over/Under

The first game of the season between the 49ers and the Rams had only 33 total points, and Los Angeles’ last four games have finished with less than 43 total points. That should continue this weekend.

NFL Pick: Under 43 (-110)

Spread

San Francisco won the season’s first matchup between these two teams by 15 points. While the 49ers will now play on the road this weekend, they should still be able to win by more than 1.5 points.

NFL Pick: 49ers -1.5 (-115)

San Francisco 49ers vs Los Angeles Rams Score Prediction

Score Prediction: 49ers 20 – Rams 16

NFL Pick: 49ers -1.5 (-115)

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More related to 49ers vs Rams

  • San Francisco 49ers Season Odds, Props and Futures
  • Los Angeles Rams Season Odds, Props and Futures
  • San Francisco 49ers vs Los Angeles Rams
#Los Angeles Rams
#NFL
#San Francisco 49ers
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