One of the most underrated matchups of Week 6 of the NFL season will take place down in Tampa, Florida. The Buccaneers are set to host the Detroit Lions, and both teams are in great shape in the standings.
Lions vs Buccaneers Picks

Take the Tampa Bay Buccaneers moneyline at +148.
Betting odds have been set for this matchup, and it’s time to start taking a close look at this matchup. Here are some Lions vs Buccaneers betting picks that you should consider making for this Week 6 showdown.
Detroit Lions vs. Tampa Bay Buccaneers Odds
Before you come up with the best Lions vs Buccaneers betting picks to make on Sunday, you need to take a close look at the NFL odds.
- Spread: Detroit is coming into this game as a three-point betting favorite.
- Total: the over/under for this game is set at 44.0 total points.
Detroit Lions vs. Tampa Bay Buccaneers Information
Detroit Lions vs Tampa Bay Buccaneers
Location of the game: Raymond James Stadium, Tampa, FL
Date & Time: Sunday, October 15th, 4:25 PM ET
Where to Watch: FOX
Detroit Lions vs. Tampa Bay Buccaneers Analysis
Detroit Lions Performance Recap and Analysis
The NFL schedule has been pretty kind to the Detroit Lions up to this point, and that’s a big reason that they have gone 4-1. The Lions are putting up some huge numbers on offense, though, as they are averaging nearly 400 yards per game.
Quarterback Jared Goff has put up some great NFL player stats as he has thrown for 1,265 yards and nine touchdowns this season. That’s a big number, and the Lions want to win this game through the air.
Key Injuries
The NFL injury report for the Lions could impact the outcome of this game, as they are hurting a bit in the secondary. Detroit is without safety C.J. Gardner Johnson and Brian Branch could be out of the lineup as well.
Betting Trends to Know
The Detroit Lions record against the spread is the same as their overall record, as they have gone 4-1. The lone time that Detroit didn’t cover the spread was in the game that they lost to the Seattle Seahawks.
Tampa Bay Buccaneers Performance Recap and Analysis
The Tampa Bay Buccaneers are in a great spot in the NFL standings, and it’s because the defense of this team has played so well. Tampa Bay’s defense holds teams to 95 rushing yards per game, prompting opponents to challenge their formidable secondary through the air.
Running the ball has still been an issue for the Buccaneers, but wide receiver Mike Evans is a star. Evans has 20 receptions for 337 yards and three touchdowns this season, and he is always looking to make a big play.
Key Injuries
The Tampa Bay Buccaneers injury report is in a good place, as the team was just off in NFL Week 5 during their bye week. Cornerback Jamel Dean is questionable for this game, and that could impact the pass defense.
Betting Trends to Know
The Buccaneers have gone 3-1 against the spread this season, and they have scored at least 20 points in three of their four games.
Detroit Lions vs. Tampa Bay Buccaneers Betting Picks
- Moneyline (Tampa Bay Buccaneers +148)
You usually want to stay away from the moneyline when making NFL picks, but it’s the best bet. Bet on the Buccaneers to pick up a massive win at home.
- Over/Under (Under 44.0)
The NFL team stats are pretty different for each team in this game, and that will create an interesting over/under line. Going with the under 44.0 is the way to go, as both teams are solid on defense.
- Spread (Tampa Bay Buccaneers +3.0)
Since we’re picking the Buccaneers to win, let’s consider betting on the point spread for this game as well. Get the three points and back the Buccaneers at home, as they will at least keep this one close.
Detroit Lions vs. Tampa Bay Buccaneers Prediction
While there are a couple of different Lions vs Buccaneers betting picks to make in this game, the moneyline really stands out. This will be one of the best NFL matchups of the weekend, and it’s going to come down to a late score.
The Detroit Lions record is better than that of the Buccaneers, but that won’t be the case after this game is over. Tampa Bay is going to get a late score as the Buccaneers come up with a massive win.
- NFL Pick: Tampa Bay Buccaneers +148
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Discover the latest stats and trends of this matchup here.